Category: Article
Dr. Albert Liu Develops Redox Polymer-Based Biosensor for Dual Glucose Monitoring and Therapeutic Applications
April 24, 2025Dr. Liu and his team have developed an advanced biosensor that uses redox polymers to improve how glucose and oxygen interact in the body.
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Dr. Anna Schwendeman and Dr. Maria Castro Work On HDL-Based Particles That Shrink Brain Tumors in Mice
April 18, 2025HDL nanodiscs carrying a Liver X Receptor agonist and CpG oligonucleotides to target glioblastoma tumors in mice. This treatment, especially when combined with radiation therapy, significantly reduced tumor size and improved long-term survival, with some mice showing no tumor recurrence upon rechallenge.
Dr. Anna & Steve Schwendeman, Alongside Dr. Maria Castro, Research a Novel Monoclonal Antibodies Delivery System
April 17, 2025Monoclonal antibody (mAb) therapeutics have become widely successful for treatment of any number of diseases. However, for certain hard-to-reach tissues, e.g., eye, brain, tumors, and joints, local delivery is desired and long-term controlled release is necessary to avoid frequent injections and poor patient compliance.
Dr. Cindy Chestek Helps Lead Design and Construction of Long-Term Brain Computer Interface
April 14, 2025In cooperation with Stanford, UM receives $19M in order to support this research. Goal of research is to assist stroke patients and allow them the ability to “speak”
Dr. Maria Castro and Dr. Pedro Lowenstein Optimize Oncolytic Viruses to Treat Various Cancers
April 14, 2025Over the past 40 years, advancements in basic virology have facilitated the development of OVs that are currently undergoing clinical evaluation. The outcomes of these translational efforts will come to fruition within the next 10 years, ultimately determining the therapeutic potential and clinical value of OVs in cancer treatment.
Dr. Xiaoming Mao and Dr. Nicholas Kotov Discover How ‘Frustration’ Builds Stronger Materials
April 7, 2025“Frustration—using these mismatched building blocks—gives rise to wonderful complexity and that complexity can be useful in providing superior material properties,” – Dr. Xiaoming Mao
Dr. Carlos Aguilar Explores Vitamin A’s Role in Long Term Stem Cell Health
April 7, 2025“Over the last hundred years, from 1950 to 2050, we’re going to see an approximate tripling of the number of people over the age of 65… We’re developing targeted therapeutics to home in on muscle stem cells without affecting other cell types and tissues,” – Dr. Carlos Aguilar
Congratulations to the Willsey Lab on The Detroit News Publishing Article on Their Research
March 25, 2025“Two University of Michigan labs are using artificial intelligence and, in one case, brain implants to help people with mobility issues, including paralysis and amputations, lead fuller lives by controlling devices with only their thoughts,” – Hannah Mackay
Dr. Carlos Aguilar’s Lab Publishes New Article On Muscle Stem Cell and Mitochondrial Function Loss
March 25, 2025Exploring the decline in number and function of adult stem cells in old age. Identifying factors that can delay or reverse age-related stem cell dysfunction
UM Researchers Drive Bold, High-Risk Cancer Discoveries at Rogel’s Forbes Institute, Yielding Promising Breakthroughs
March 21, 2025“There was a very provocative idea in the field that these cells come into the blood early on…The tumor was removed early, so why are these cells re-emerging after 20 years? The cells have to come from the DCIS. But how do we connect the dots? If you look at blood from DCIS patients, do you find tumor cells in the blood?” – Dr. Sunitha Nagrath
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