
Single Cell Technologies
This cluster focuses on the development of methods and technologies to probe a single cell.

This goal of this cluster is to build a synergistic scientific and technological platform to investigate one of the most critical building blocks of any biological system – a cell. Through the convergence of biology, computational approaches and engineering, the cluster addresses fundamental biological questions on cellular heterogeneity by developing integrated approaches and technologies to isolate, preserve, characterize and expand rare cells. This approach will enable investigation of basic biological components of single cells at a higher resolution and holds the promise of transforming the study, diagnosis and treatment of every disease. The cluster builds upon an existing ecosystem of UM investigators with complementary research excellence and active collaborations from engineering, physical sciences, life sciences and the medical school.
Recent Publications
Three-dimensional (3D) adipose tissue organoids for disease modeling. Lipid (red), actin (green), nucleus (blue).

Cell in an engineered scaffold

Related Press Releases & Articles

- April 7 @ 1:00 pm
BI Distinguished Lectureship Series with Dr. David A. Weitz
Join us on April 7 for a Distinguished Lecture by Dr. David A. Weitz.

- April 1, 2021 / Article
Recent BI Publications
Publications from BI Research Groups in March

- March 30 @ 3:30 pm
BI Distinguished Lectureship Series with Dr. James Kirkland
Join us on March 30 for a Distinguished Lecture by Dr. James Kirkland from @MayoClinic on his research on aging, cellular senescence and age-related diseases.

- March 1, 2021 / Article
Recent BI Publications
Publications from BI Research Groups in February

- February 23, 2021 / Award
Call for Nominations: 2020-21 BI Innovator Awards
Nomination Deadline: March 31, 2021
The goal of the Innovator Awards is to recognize BI members who are actively participating in the research, innovation and translational ecosystem at BI and making a difference in our community.
This past year has been a strong reminder that the excellence and strength of our institute transcend research and innovation. BI members are continually contributing to their community through exceptional service and commitment to causes and activities that extend beyond science.
As in previous years, three Innovator Awards will be granted, with one awarded at the faculty, graduate student and postdoctoral level, respectively.
This year, we will be adding a fourth Innovator Award to recognize a person (graduate student, undergraduate student, faculty, postdoctoral fellow or staff) who is making a difference in the BI community, in particular, as it relates to contributions that extend beyond the topic of their scientific work. Examples of such exceptional achievement might include creation and launch or leadership in new programs and initiatives related to outreach, mentoring programs, diversity, equity and inclusion, well-being.

- February 1, 2021 / Article
Recent BI Publications
Publications from BI Research Groups in January

- January 29, 2021 / Article
S. Nagrath Lab develops new microfluidic chip to capture and investigate exosomes
The Sunitha Nagrath lab reports on their work to capture natural killer cells and harvest exosomes to investigate their potential for battling cancer cells.

- December 1, 2020 / Article
Recent BI Publications
Publications from BI Research Groups in November

- October 30, 2020 / Article
Recent BI Publications
Publications from BI Research Groups in October

- October 12, 2020 / Award
Kotov Recipient of Alpha Chi Sigma Award
For his work in self-assembly processes at the nanoscale, Nick Kotov received the 2020 Alpha Chi Sigma Award.

- September 30, 2020 / Article
Recent BI Publications
Publications from BI Research Groups in September

- July 31, 2020 / Article
Recent BI Publications
Publications from BI Research Groups in July

- July 9, 2020 / Article
Study by Deepak Nagrath and Sunitha Nagrath Labs propose new strategy to target pancreatic cancer
Study by Deepak Nagrath and Sunitha Nagrath Labs propose new strategy to target pancreatic cancer

- May 7, 2020 / Award
Deepak Nagrath Named Forbes Scholar
Congratulations to Deepak Nagrath on being named one of the Rogel Cancer Center’s 2020 Forbes Scholars. Nagrath is using genetic and clinical data from patients to identify mutations in ovarian cancer cells.

- March 2, 2020 / Award
2020 BI Innovator Awardees
Congratulations to the 2020 BI Innovator Award Recipients. BI Innovator awards recognize members of the BI research community who are active participants in the research, innovation and translational ecosystem at BI.
The 2020 awardees will be featured speakers at the BI Research Day on March 18.

- January 31, 2020 / Article
Recent BI Publications
Publications from BI Research Groups in January

- January 2, 2020 / Article
Recent BI Publications
Publications from BI Research Groups in December

- December 18, 2019 / Award
BI Teams Receive Biosciences Initiative Awards
Three major research initiatives projects were awarded to BI faculty in the latest round of funding from the Biosciences Initiative

- December 12, 2019 / Article
Call for Nominations for BI Innovator Awards
The Biointerfaces Institute seeks nominations for its annual BI Innovator Awards.
The goal of the Innovator Award is to recognize faculty, graduate student and postdoctoral researchers who are active contributors to the interdisciplinary research, innovation and translational ecosystem at BI.

- October 31, 2019 / Article
Recent BI Publications
Publications from BI Research Groups in October