Single Cell Technologies

The inaugural BI Research Day and third annual microposter session was a huge success! Thank you to all who participated.

Join us for the inaugural BI Research Day and third annual Microposter Session on March 20, 2019.

The inaugural 2019 BI Innovator Awards are awarded to Tim Bruns, Yichun Wang and Rose Cersonsky.

Evan Keller and collaborators from the Department of Urology publish a new article on a surgical grafting technique, for direct implantation of human cancer cells into the bladder lumen.

The article titled “A Surgical Orthotopic Approach to Study the Invasive Progression of Human Bladder Cancer” appears in Nature Protocol.

Recent publications from BI Research Groups

The Biointerfaces Institute seeks nominations for its inaugural round of BI Innovator Awards.

The goal of the Innovator Award is to recognize faculty, graduate student and postdoctoral researchers who are active contributors to the interdisciplinary research, innovation and translational ecosystem at BI.

Sunitha Nagrath is the recipient of the 2018 Analytical Chemistry Young Innovator Award. The award honors the contributions of an individual who has demonstrated exceptional technical advancement and innovation in the field of microfluidics or nanofluidics in his or her early career.

The article entitled “Profiling Heterogeneous Circulating Tumor Cells (CTC) Populations in Pancreatic Cancer Using a Serial Microfluidic CTC Carpet Chip” appears in Advanced Biosystems.

The Henry Russel Lectureship is awarded annually to a faculty member with exceptional achievements in research, scholarship or creative endeavors, as well as an outstanding record of teaching, mentoring and service.

Thank you to all of the poster presenters who attended the BIRG 2nd Microposter Session and congratulations to our winners!

Carlos Aguilar is one of the recipients of the 2018 3M Non-Tenured Faculty Awards. Awarded by 3M Corporation, this award recognizes junior faculty who demonstrate outstanding research, experience, teaching and academic leadership.

Patricia Schnepp, PhD and Vishwanath Sankarasubramanian, PhD receive Postdoctoral Translational Scholars Program (PTSP) Awards from MICHR.

Carlos Aguilar, Assistant Professor of Biomedical Engineering, and his research group recently joined BI. The Nano-Omic-Bio-Engineering Lab (NOBEL) is working on developing new approaches and tools to understand and investigate skeletal muscles.

A research article from Sunitha Nagrath’s lab, in collaboration with the Keller, Wicha and Simeone groups, entitled “High-Throughput Microfluidic Labyrinth for Label-free Isolation of Circulating Tumor Cells” was published in Cell Systems.

In work started during his time at Rice University, Deepak Nagrath continues to research cancer cell metabolism and how cancer cells interact. Learning how the cells communicate could lead to new targets for more effective treatments than those currently is use.

Currently being used in a breast cancer clinical trial to isolate cancer cells in blood, Sunitha Nagrath and Max Wicha led the development of a hydrodynamic maze called the labyrinth chip. With its innovative design, the labyrinth chip allows researchers to capture cells for molecular analysis so they can know what to target with treatments.

“Nitric Oxide: The Forgotten Child of Tumor Metabolism” appears in Trends in Cancer

The Single Cell Analysis Core, led by co-directors Evan Keller and Sunitha Nagrath, is using blood tests to isolate cancer cells to better understand the disease. In what they hope to become routine practice, “liquid biopsies” are being analyzed to provide an early determination of whether patients may need additional treatment.

Sunitha Nagrath discusses microfluidic devices developed in her lab to capture cancer cells and their promise to develop liquid biopsy approaches to diagnosing cancer.