BioInnovations in Brain Cancer
About the BioInnovations in Brain Cancer Initiative (BIBC)
The BIBC initiative nucleated at a Biointerfaces Institute Challenge workshop in 2013 and received follow-on funding from the Biosciences Initiative in 2019. The BIBC team represents an interdisciplinary group of technologists and brain cancer experts who are actively collaborating to make an impact on brain cancer patients.
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James Moon
J G Searle Professor, Professor of Pharmaceutical Sciences, Chair, Department of Pharmaceutical Sciences, College of Pharmacy and Professor of Biomedical Engineering, Medical School and College of Engineering Research Focus: Advanced Materials and Drug Delivery, BioInnovations in Brain Cancer Contact Information:[email protected]The Moon Group develops therapeutics and diagnostics at the interface of immunology and engineering. Research addresses drug delivery systems for enhancing delivery of antigen and adjuvant to lymphoid organs and manipulating immune functions in the context of cancer, infectious diseases, and autoimmunity.
Steven Schwendeman
Ara G Paul Professor of Pharmaceutical Sciences, Professor of Pharmaceutical Sciences, College of Pharmacy and Professor of Biomedical Engineering, Medical School and College of Engineering Research Focus: BioInnovations in Brain Cancer, Advanced Materials and Drug Delivery Contact Information:[email protected]The Schwendeman Group develops advanced polymer-based controlled drug delivery approaches including vaccine delivery from poly(lactic-co-glycolic acid) (PLGA); PLGA nanoparticle formulation; and development of mucoadhesive polymers/formulations for intraoral and intranasal delivery.
Deepak Nagrath
Professor of Biomedical Engineering, College of Engineering and Medical School Research Focus: BioInnovations in Brain Cancer, Cell and Tissue Engineering, Single Cell Technologies Contact Information:[email protected]The Nagrath lab focuses on both experimental and theoretical aspects of Cellular and Molecular Tissue Engineering, Metabolic Engineering, and Biomedicine with emphasis on clinical applications. Our research interests lie in the systems biology of metabolic diseases, specifically cancer.
Jouha Min
Assistant Professor of Chemical Engineering, College of Engineering Research Focus: Cell and Tissue Engineering, Advanced Materials and Drug Delivery, BioInnovations in Brain Cancer, Nanotechnology Contact Information:[email protected]The Min lab focuses on developing and implementing general methodologies to study complex material-biology interactions in both 3D space and time, in diverse contexts, laying the scientific foundation for transformative advances in disease diagnosis, treatment, and prevention. Their research encompasses a broad range of biomedical topics, such as cancer, sepsis, traumatic brain injury, tissue damage/repair, pathogenic infections, and immune engineering.
Peter Tessier
Albert M Mattocks Professor of Pharmacy, Professor of Pharmaceutical Sciences, College of Pharmacy and Professor of Chemical Engineering, College of Engineering Research Focus: BioInnovations in Brain Cancer, Advanced Materials and Drug Delivery, Nanotechnology Contact Information:[email protected]The Tessier lab aims to develop next generation technologies for designing, discovering, engineering, characterizing, formulating and delivering biologics ranging from small affinity peptides to large monoclonal antibodies for molecular imaging, diagnostic and therapeutic applications.
Guizhi (Julian) Zhu
Ara Garo Paul Professor, Associate Professor of Pharmaceutical Sciences and Associate Chair, College of Pharmacy Research Focus: BioInnovations in Brain Cancer Contact Information:[email protected]The Zhu lab is focused on the development of nucleic acid therapeutics and vaccines for cancer and immune disorders.
Toshiro Hara
Assistant Professor of Neurosurgery, Medical School Research Focus: BioInnovations in Brain Cancer Contact Information:[email protected]The Hara laboratory is focused on the study of understanding the intratumoral heterogeneity as well as the mechanisms of cellular communication within this intratumoral microenvironment as it relates to glioblastoma. We work at the intersection of human biology, model system, and single-cell genomics to understand how cells interact and communicate with their surrounding environment and how cells process environmental inputs to exert functions relevant to the malignant properties of glioblastoma.
Joerg Lahann
Wolfgang Pauli Collegiate Professor of Chemical Engineering, Professor of Chemical Engineering, Professor of Materials Science and Engineering, Professor of Biomedical Engineering, Professor of Macromolecular Science and Engineering and Academic Program Director, Biointerfaces Institute, College of Engineering Research Focus: Advanced Materials and Drug Delivery, Single Cell Technologies, BioInnovations in Brain Cancer Contact Information:[email protected]Research in the Lahann Lab focuses on surface engineering, advanced polymers, biomimetic materials, engineered stem cell microenvironments, drug delivery, and nano-scale self-assembly.
Anna Schwendeman
Professor of Pharmaceutical Sciences Research Focus: BioInnovations in Brain Cancer, Nanotechnology Contact Information:[email protected]Schwendeman’s principal research interest is to understand how phospholipid composition of high-density lipoprotein (HDL) affects its potency and to design short synthetic peptides that mimic various functions of Apolipoprotein A-I, the main HDL protein. Laboratory work focuses on HDL for treatment of sepsis, Alzheimer’s disease, complications of diabetes, lupus and other autoimmune diseases and using synthetic HDL nanoparticles for targeted drug delivery purposes and designing artificial HDL based on gold nanoparticles.