Nanotechnology

Research Publications

Scholarly Contributions

BI researchers are at the forefront of their field and combine their expertise to tackle the most complex biomedical questions. They are active contributors to the scholarly mission of our institute and training the next generation of scientists.

BI Impact

BI researchers are active contributors to the university’s research mission: engaging in scientific discovery and entrepreneurship across the institute and the entire campus. At BI, we are making scholarly impact and technological strides, while training the next generation of biomedical engineers.

Research Accomplishments

$98M

in research expenditures since 2012

$1.35M

Distribution In Seed Funding To 20 Multi-Disciplinary Teams

7

Department Challenges Organized That Brought Together 300+ Participants

Since 2012 BI Researchers Have Participated In

1000+ Publications
100,000+ Citations

130
Inventions

85
Issued Patents

6
New Startups

Recent Publications

Battle of GLP-1 delivery technologies (A. Schwendeman and S. Schwendeman)
Macrophages: The bridge between inflammation resolution and tissue repair? (Giannobile)
Dynamic microRNA activity identifies therapeutic targets in trastuzumab‐resistant HER2+ breast cancer (Shea)
Universal folding pathways of polyhedron nets (Glotzer)
Surface-initiated RAFT polymerization from vapor-based polymer coatings (Lahann)
Direct all-atom molecular dynamics simulations of the effects of short chain branching on polyethylene oligomer crystal nucleation (Larson)
Quantitative simulation of extracellular single unit recording from the surface of cortex (Chestek and Lempka)
Nonmonotonic scission and branching free energies as functions of hydrotrope concentration for charged micelles (Larson)
Understanding and overcoming trade-offs between antibody affinity, specificity, stability and solubility (Tessier)
Variability in the location of high frequency oscillations during prolonged intracranial EEG recording (Stacey and Chestek)
Infliximab biosimilars in the age of personalized medicine (A. Schwendeman and S. Schwendeman)
Local immunomodulation with anti-inflammatory cytokine-encoding lentivirus enhances functional recovery after spinal cord injury (Shea)
Electrical stimulation of renal nerves for modulating urine glucose excretion in rats (Bruns)
Plasmonic biomimetic nanocomposite with spontaneous subwavelength structuring as broadband absorbers (Kotov)
A simple, inexpensive method for subcortical stereotactic targeting in nonhuman primates (Chestek)
Synthetic high-density lipoprotein nanoconjugate targets neuroblastoma stem cells, blocking migration and self-renewal (A. Schwendeman)
Materials engineering of high-performance anodes as layered composites with self-assembled conductive networks (Kotov)
Effect of surface charge and hydrophobicity onphospholipid-nanoparticle corona formation: A molecular dynamics simulation study (Larson)
Asparagine and glutamine: Co-conspirators fueling metastasis (Wicha)
Retrievable hydrogels for ovarian follicle transplantation and oocyte collection (Shea)
Evaluation of biomaterial scaffold delivery of IL-33 as a localized immunomodulatory agent to support cell transplantation in adipose tissue (Shea)
Dual TLR agonist nanodiscs as a strong adjuvant system for vaccines and immunotherapy (Moon and A. Schwendeman)
Compartmentalized microhelices prepared via electrohydrodynamic cojetting (Lahann)
Elimination of established tumors with nanodisc-based combination chemoimmunotherapy (Moon and A. Schwendeman)
Microporous polymer scaffolds for the transplantation of embryonic stem cell derived pancreatic progenitors to a clinically translatable site for the treatment of Type I diabetes (Shea)
MP70-06 micro-and macro-fluidic models of prostate cancer metastasis (Keller)
Mapping Disorder in Entropically Ordered Crystals (Glotzer)
Prediction of striped cylindrical micelles (SCMs) formed by dodecyl-β-D-maltoside (DDM) surfactants (Larson)
Robust inflammatory and fibrotic signaling following volumetric muscle loss: a barrier to muscle regeneration (Aguilar)
Circulating Tumor Cells: Diagnostic and Therapeutic Applications (S. Nagrath)
Antibacterial metal oxide nanoparticles: Challenges in interpreting the literature (Kotov and Van Epps)
Strain fields in repulsive colloidal crystals (Glotzer)
Bacteria-like mesoporous silica-coated gold nanorods for positron emission tomography and photoacoustic imaging-guided chemo-photothermal combined therapy (Moon)
Inertio-capillary cross-streamline drift of droplets in Poiseuille flow using dissipative particle dynamics simulations (Larson)
Efficient phase diagram sampling by active learning (Glotzer)
Chemo-photothermal therapy combination elicits anti-tumor immunity against advanced metastatic cancer (A. Schwendeman and Moon)
Transcription factor 21 (Tcf21) promotes proinflammatory interleukin 6 expression and extracellular matrix remodeling in visceral adipose stem cells (Chun)
Introduction: Liquid Biopsies (S. Nagrath)
Heterogeneity of human breast stem and progenitor cells as revealed by transcriptional profiling (Wicha)
Direct measurement of bipolar cell responses to electrical stimulation in wholemount mouse retina (Weiland)
Subcutaneous Nanodisc Vaccination with Neoantigens for Combination Cancer Immunotherapy (Moon and A. Schwendeman)
Bridging dynamics of telechelic polymers between solid surfaces (Larson)
Biomaterial scaffolds as pre-metastatic niche mimics systemically alter the primary tumor and tumor microenvironment (Shea)
Flexible microelectrode array for interfacing with the surface of neural ganglia (Bruns)
3D Jet Writing: Functional Microtissues Based on Tessellated Scaffold Architectures (Lahann, Luker and Krebsbach)
Progress of multi-compartmental particles for medical applications (Lahann)
High-density lipoprotein-mimicking nanodiscs carrying peptide for enhanced therapeutic angiogenesis in diabetic hindlimb ischemia (Moon and A. Schwendeman)
Unusual multiscale mechanics of biomimetic nanoparticle hydrogels (Kotov and Glotzer)
Seizure prediction is possible–Now let’s make it practical (Stacey)
Capacitive coupling synchronizes autonomous microfluidic oscillators (Takayama)
Apoptosis-induced CXCL5 accelerates inflammation and growth of prostate tumor metastases in bone (Keller and Shea)
Tibial nerve stimulation to drive genital sexual arousal in an anesthetized female rat (Bruns)
Shapes within shapes: how particles arrange inside a cavity (Glotzer)
The future of radiobiology (Lombaert)
Circulating tumor cell-derived organoids: Current challenges and promises in medical research and precision medicine (S. Nagrath)
Role of thickness confinement on relaxations of the fast component in a miscible A/B blend (Green)
Techniques to produce and culture lung tumor organoids (Takayama)
Self-assembly of inorganic nanoparticles: Ab ovo (Kotov)
Time-Frequency analysis of increases in vaginal blood perfusion elicited by long-duration pudendal neuromodulation in anesthetized rats (Bruns)
Designing 3-D adipospheres for quantitative metabolic study (Chun and Takayama)
Structure, mechanics, and instability of fibrin clot infected with Staphylococcus epidermidis (Solomon and Van Epps)
Effect of synthetic high density lipoproteins modification with polyethylene glycol on pharmacokinetics and pharmacodynamics (A. Schwendeman)
The key role of extracellular vesicles in the metastatic process (D. Nagrath)
Modeling of interactions between cancer stem cells and their microenvironment: Predicting clinical response (Wicha)
Closed-loop continuous hand control via chronic recording of regenerative peripheral nerve interfaces (Chestek)
Robust tactile sensory responses in finger area of primate motor cortex relevant to prosthetic control (Chestek and Stacey)

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