Research Publications
Scholarly Contributions
BI researchers are at the forefront of their field and combine their expertise to tackle the most complex biomedical questions. They are active contributors to the scholarly mission of our institute and training the next generation of scientists.
BI Impact
BI researchers are active contributors to the university’s research mission: engaging in scientific discovery and entrepreneurship across the institute and the entire campus. At BI, we are making scholarly impact and technological strides, while training the next generation of biomedical engineers.
Research Accomplishments
$98M
in research expenditures since 2012
$1.7M
Distribution In Seed Funding To 25+ Multi-Disciplinary Teams
9
Department Challenges Organized That Brought Together 350+ Participants
Since 2012 BI Researchers Have Participated In
1000+ Publications
100,000+ Citations
150+
Inventions
98
Issued Patents
7
New Startups
Recent Publications
View a listing of the most recent BI publications here
Advanced Materials and Drug Delivery
- Assessment of biosimilarity under native and heat-stressed conditions: rituximab, bevacizumab, and trastuzumab originators and biosimilars (A. Schwendeman)
- Multifaceted assessment of rituximab biosimilarity: The impact of glycan microheterogeneity on Fc function (A. Schwendeman & S. Schwendeman)
- Potential of electrospun cationic BSA fibers to guide osteogenic MSC differentiation via surface charge and fibrous topography (Lahann)
- Feedback controlled photolytic gas phase nitric oxide delivery from S-nitrosothiol-doped silicone rubber films (S. Schwendeman)
- Long-acting reversible contraception by effervescent microneedle patch (S. Schwendeman)
- Synthetic high-density lipoprotein nanoparticles for the treatment of Niemann–Pick diseases (A. Schwendeman)
- Unique impacts of methionine oxidation, tryptophan oxidation and asparagine deamidation on antibody stability and aggregation (Tessier)
- Directed evolution methods for overcoming trade‐offs between protein activity and stability (Tessier)
- Engineered fibrillar fibronectin networks as three-dimensional tissue scaffolds (Lahann, Luker & Wicha)
- Extracellular trap‐mimicking DNA‐histone mesostructures synergistically activate dendritic cells (Moon)
- Positron emission tomography-guided photodynamic therapy with biodegradable mesoporous silica nanoparticles for personalized cancer immunotherapy (Moon)
- Predicting drug release kinetics from nanocarriers inside dialysis bags (A. Schwendeman & S. Schwendeman)
- Wettability engendered templated self-assembly (WETS) for the fabrication of biocompatible, polymer–polyelectrolyte janus particles (Tuteja)
Cell and Tissue Engineering
- Characterization of macrophages infiltrating peri‐implantitis lesions (Giannobile)
- Co-culture of functionally enriched cancer stem-like cells and cancer-associated fibroblasts for single-cell whole transcriptome analysis (Wicha)
- Developing a model for integrating professional practice and evidence-based teaching practices into BME curriculum (Shea)
- New labyrinth microfluidic device detects circulating tumor cells expressing cancer stem cell marker and circulating tumor microemboli in hepatocellular carcinoma (S. Nagrath)
- Research for prevention of oral/dental diseases: how far have we come? (Giannobile)
- Cell-based therapies for alveolar bone and periodontal regeneration: Concise review (Giannobile)
- Characterization of bulk rigidity of rigid red blood cell populations in sickle cell patients using a parameterization model of ektacytometry (Eniola-Adefeso)
- Lactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts (D. Nagrath)
- PLG bridge implantation in chronic SCI promotes axonal elongation and myelination (Shea)
- The effect of rigid red blood cells on platelet adhesion in blood flow and implications in sickle cell disease (Eniola-Adefeso)
- Immuno-isolating dual poly(ethylene glycol) capsule prevents cancer cells from spreading following mouse ovarian tissue auto-transplantation (Shea)
- Isolation and profiling of circulating tumor‐associated exosomes using extracellular vesicular lipid–protein binding affinity based microfluidic device (S. Nagrath)
- Macrofluidic recirculating model of skeletal metastasis (Keller)
- Model particulate drug carriers modulate leukocyte adhesion in human blood flows (Eniola-Adefeso)
- Precision health for breast cancer metastasis: biomaterial scaffolds as an engineered metastatic niche to define, study, and monitor metastatic progression (Shea & Wicha)
- Towards systems tissue engineering: elucidating the dynamics, spatial coordination, and individual cells driving emergent behaviors (Shea)
Nanotechnology
- Analysis of self-assembly pathways with unsupervised machine learning algorithms (Glotzer)
- Bio-inspired nanocomposite membranes for osmotic energy harvesting (Kotov)
- Chemo- and thermomechanically configurable 3D optical metamaterials constructed from colloidal nanocrystal assemblies (Kotov)
- Multiscale modeling of sub-entanglement-scale chain stretching and strain hardening in deformed polymeric glasses (Larson)
- Pressure in rigid body molecular dynamics (Glotzer)
- Self-assembly of chiral nanoparticles into semiconductor helices with tunable near-infrared optical activity (Kotov)
- Dendrimer ligand directed nanoplate assembly (Glotzer)
- HOOMD-blue: A Python package for high-performance molecular dynamics and hard particle Monte Carlo simulations (Glotzer)
- Unified memory in HOOMD-blue improves node-level strong scaling (Glotzer)
- Yield stress and rheology of a self-associating chitosan solution (Solomon)
- Assessing the range of validity of current tube models through analysis of a comprehensive set of star–linear 1,4-polybutadiene polymer blends (Larson)
- Immobilization of calcium oxide onto polyacrylonitrile (PAN) fibers as a heterogeneous catalyst for biodiesel production (Larson)
- Looped liquid-liquid coexistence in protein crystallization (Glotzer)
- Origin of chiroptical activity in nanorod assemblies (Kotov)
- Single- and multi-component chiral supraparticles as modular enantioselective catalysts (Kotov)
Neural Engineering
- An update on retinal prostheses (Weiland)
- Emerging roles of network analysis for epilepsy (Stacey)
- Graph theory for EEG: can we learn to trust another black box? (Stacey)
- High density microelectrode recording predicts span of therapeutic tissue activation volumes in subthalamic deep brain stimulation for Parkinson disease (Chestek)
- Spatial models of cell distribution in human lumbar dorsal root ganglia (Bruns & Lempka)
- Estimating risk for future intracranial, fully implanted, modular neuroprosthetic systems: a systematic review of hardware complications in clinical deep brain stimulation and experimental human intracortical arrays (Chestek)
- Ultracompliant carbon nanotube direct bladder device (Bruns)