Research Publications
Scholarly Contributions
BI researchers are at the forefront of their field and combine their expertise to tackle the most complex biomedical questions. They are active contributors to the scholarly mission of our institute and training the next generation of scientists.
BI Impact
BI researchers are active contributors to the university’s research mission: engaging in scientific discovery and entrepreneurship across the institute and the entire campus. At BI, we are making scholarly impact and technological strides, while training the next generation of biomedical engineers.
Research Accomplishments
$98M
in research expenditures since 2012
$1.7M
Distribution In Seed Funding To 25+ Multi-Disciplinary Teams
9
Department Challenges Organized That Brought Together 350+ Participants
Since 2012 BI Researchers Have Participated In
1000+ Publications
100,000+ Citations
150+
Inventions
98
Issued Patents
7
New Startups
Recent Publications
View a listing of the most recent BI publications here
Advanced Materials and Drug Delivery
- Emerging methods in therapeutics using multifunctional nanoparticles (Lahann)
- Synthetic HDL nanoparticles delivering docetaxel and CpG for chemoimmunotherapy of colon adenocarcinoma (Moon & A. Schwendeman)
- Effect of manufacturing variables and raw materials on the composition-equivalent PLGA microspheres for 1-month controlled release of leuprolide (S. Schwendeman)
- Microencapsulation of luteinizing hormone-releasing hormone agonist in poly (lactic-co-glycolic acid) microspheres by spray drying (A. Schwendeman & S. Schwendeman)
- Structural analysis of lecithin:cholesterol acyltransferase bound to high density lipoprotein particles (A. Schwendeman)
Cell and Tissue Engineering
- Cellular, transcriptomic and isoform heterogeneity of breast cancer cell line revealed by full-length single-cell RNA sequencing (Keller & Wicha)
- Efficacy and effect of cabozantinib on bone metastases in treatment-naïve castration-resistant prostate cancer (Keller)
- Electron transport chain activity is a predictor and target for venetoclax sensitivity in multiple myeloma (D. Nagrath)
- The influence of red blood cell deformability on hematocrit profiles and platelet margination (Eniola-Adefeso)
- Tuning macrophage phenotype to mitigate skeletal muscle fibrosis (Aguilar)
- Osteoclast-mediated bone resorption is controlled by a compensatory network of secreted and membrane-tethered metalloproteinases (Keller)
- Polycistronic delivery of IL-10 and NT-3 promote oligodendrocyte myelination and functional recovery (Shea)
- Identification of osteoclast-osteoblast coupling factors in humans reveals links between bone and energy metabolism (Weivoda)
- Liquid chromatography methods for separation of polar and charged intracellular metabolites for 13C metabolic flux analysis (D. Nagrath)
- Metabolic reprogramming and vulnerabilities in cancer (D. Nagrath)
- Quantifying metabolic transfer mediated by extracellular vesicles using Exo-MFA: an integrated empirical and computational platform (D. Nagrath)
Nanotechnology
- Cooperative switching in large‐area assemblies of magnetic janus particles (Glotzer & Lahann)
- Injectable MMP-responsive nanotube-modified gelatin hydrogel for dental infection ablation (A. Schwendeman)
- Molecularly engineered nanobodies for tunable pharmacokinetics and drug delivery (Greineder)
- Chiral 2D organic inorganic hybrid perovskite with circular dichroism tunable over wide wavelength range (Kotov)
- Effect of defective microstructure and film thickness on the reflective structural color of self-assembled colloidal crystals (Glotzer & Solomon)
- High signal-to-noise, non-bleaching imaging with plasmonic nanoparticles (Lee)
- Selective targeting of nanomedicine to inflamed cerebral vasculature to enhance the blood–brain barrier (Greineder)
- Pinning dislocations in colloidal crystals with active particles that seek stacking faults (Glotzer)
Neural Engineering
- A regenerative peripheral nerve interface allows real-time control of an artificial hand in upper limb amputees (Chestek)
- Epidynamics characterize and navigate the map of seizure dynamics (Stacey)
- Toward guiding principles for the design of biologically-integrated electrodes for the central nervous system (Chestek)