Research Publications
Scholarly Contributions
BI researchers are at the forefront of their field and combine their expertise to tackle the most complex biomedical questions. They are active contributors to the scholarly mission of our institute and training the next generation of scientists.
BI Impact
BI researchers are active contributors to the university’s research mission: engaging in scientific discovery and entrepreneurship across the institute and the entire campus. At BI, we are making scholarly impact and technological strides, while training the next generation of biomedical engineers.
Research Accomplishments
$98M
in research expenditures since 2012
$1.35M
Distribution In Seed Funding To 20 Multi-Disciplinary Teams
7
Department Challenges Organized That Brought Together 300+ Participants
Since 2012 BI Researchers Have Participated In
1000+ Publications
100,000+ Citations
150+
Inventions
98
Issued Patents
7
New Startups
Recent Publications
View a listing of the most recent BI publications here
Advanced Materials and Drug Delivery
- High‐throughput scaffold system for studying the effect of local geometry and topology on the development and orientation of sprouting blood vessels (Lahann)
- Three-dimensional microenvironmental priming of human mesenchymal stem cells in hydrogels facilitates efficient and rapid retroviral gene transduction via accelerated cell cycle synchronization (Moon)
- Inkjet-printed micro-calibration standards for ultraquantitative Raman spectral cytometry (A. Schwendeman and Tuteja)
Cell and Tissue Engineering
- Cargo-less nanoparticles program innate immune cell responses to toll-like receptor activation (Shea)
- Intravascular innate immune cells reprogrammed via intravenous nanoparticles to promote functional recovery after spinal cord injury (Shea)
- Knockdown of Notch1 inhibits nasopharyngeal carcinoma cell growth and metastasis via downregulation of CCL2, CXCL16, and uPA (Keller)
- Microporous scaffolds support assembly and differentiation of pancreatic progenitors into β-cell clusters (Shea)
- Biological factors involved in alveolar bone regeneration (Giannobile)
- Characterization of macrophage polarization in periodontal disease (Giannobile)
- Dynamic genome-scale cell-specific metabolic models reveal novel inter-cellular and intra-cellular metabolic communications during ovarian follicle development (Shea)
- Effect of cyclin E overexpression on resistance to trastuzumab and phosphorylation of SMAD3 in HER2+ breast cancer (Shea)
- Targeting cathepsin K diminishes prostate cancer establishment and growth in murine bone (Keller)
- Dietary polyunsaturated fatty acids modulates adipose Secretome and is associated with changes in mammary epithelial stem cell self-renewal (Wicha)
- Hydro-Seq enables contamination-free high-throughput single-cell RNA-sequencing for circulating tumor cells (S. Nagrath and Wicha)
- Optimizing PLG nanoparticle-peptide delivery platforms for transplantation tolerance using an allogeneic skin transplant model (Shea)
- Personalized scaffolding technologies for alveolar bone regenerative medicine (Giannobile)
- SUN-099 fibro-adipogenic remodeling of the diaphragm in obesity-associated respiratory dysfunction (Chun)
- Targeted Notch1 inhibition with a Notch1 antibody, OMP‐A2G1, decreases tumor growth in two murine models of prostate cancer in association with differing patterns of DNA damage response gene expression (Keller)
Nanotechnology
- Energy Landscapes for Digital Alchemy (Glotzer)
- Entropic colloidal crystallization pathways via fluid–fluid transitions and multidimensional prenucleation motifs (Glotzer)
- Letter to the Editor: Modeling the nonmonotonic time-dependence of viscosity bifurcation in thixotropic yield-stress fluids (Larson & Solomon)
- Modeling Intercolloidal Interactions Induced by Adsorption of Mobile Telechelic Polymers onto Particle Surfaces (Larson)
- Terahertz circular dichroism spectroscopy of biomaterials enabled by kirigami polarization modulators (Kotov)
- Topological Order in Densely Packed Anisotropic Colloids (Glotzer)
- freud: A software suite for high throughput analysis of particle simulation data (Glotzer)
- Colloidal gel elasticity arises from the packing of locally glassy clusters (Solomon)
- Non-resonant enhancement of second-harmonic generation in a dielectric particle with a nanostructured nonlinear metamaterial shell (Kotov)
- Phase behavior and design rules for plastic colloidal crystals of hard polyhedra via consideration of directional entropic forces (Glotzer)
- Plasmonic nanoparticles with supramolecular recognition (Kotov)
Neural Engineering
- Evoked potentials recorded from the spinal cord during neurostimulation for pain: a computational modeling study (Lempka)
- Behavioral monitoring and neuromodulation of feline voiding function (Bruns)
- Kilohertz frequency stimulation of renal nerves for modulating blood glucose concentration in diabetic rats (Bruns)
- Microneedle penetrating array with axon-sized dimensions for cuff-less peripheral nerve interfacing (Bruns and Chestek)
- Neural correlates of error processing during grasping with invasive brain-machine interfaces (Chestek)
- Real-time bladder pressure estimation for closed-loop control in a detrusor overactivity model (Bruns)
- Simultaneous impedance measurements of the Utah electrodes array : A finite element method analysis (Weiland)