Research Publications
Scholarly Contributions
BI researchers are at the forefront of their field and combine their expertise to tackle the most complex biomedical questions. They are active contributors to the scholarly mission of our institute and training the next generation of scientists.
BI Impact
BI researchers are active contributors to the university’s research mission: engaging in scientific discovery and entrepreneurship across the institute and the entire campus. At BI, we are making scholarly impact and technological strides, while training the next generation of biomedical engineers.
Research Accomplishments
$98M
in research expenditures since 2012
$1.7M
Distribution In Seed Funding To 25+ Multi-Disciplinary Teams
9
Department Challenges Organized That Brought Together 350+ Participants
Since 2012 BI Researchers Have Participated In
1000+ Publications
100,000+ Citations
150+
Inventions
98
Issued Patents
7
New Startups
Recent Publications
View a listing of the most recent BI publications here
Advanced Materials and Drug Delivery
- Multilamellar vaccine particle elicits potent immune activation with protein antigens and protects mice against ebola virus infection (Moon)
- Engineering patient-specific cancer immunotherapies (Moon & A. Schwendeman)
- High‐density lipoprotein in lupus: Disease biomarkers and potential therapeutic strategy (A. Schwendeman)
- Hyaluronic acid–bilirubin nanomedicine for targeted modulation of dysregulated intestinal barrier, microbiome and immune responses in colitis (Moon)
- Mimetic sHDL nanoparticles: A novel drug-delivery strategy to target triple-negative breast cancer (Moon & A. Schwendeman)
- Survey of clinical translation of cancer nanomedicines—Lessons learned from successes and failures (A. Schwendeman)
Cell and Tissue Engineering
- Autogenous soft tissue grafting for periodontal and peri‐implant plastic surgical reconstruction (Giannobile)
- Biologics‐based regenerative technologies for periodontal soft tissue engineering (Giannobile)
- Extracellular matrix‐based scaffolding technologies for periodontal and peri‐implant soft tissue regeneration (Giannobile)
- High frequency spectral ultrasound imaging to detect metastasis in implanted biomaterial scaffolds (Shea)
- Living cell‐based regenerative medicine technologies for periodontal soft tissue augmentation (Giannobile)
- Microporous scaffolds loaded with immunomodulatory lentivirus to study the contribution of immune cell populations to tumor cell recruitment in vivo (Shea)
- Primary prostate cancer educates bone stroma through exosomal pyruvate kinase M2 to promote bone metastasis (Keller)
- SNV identification from single-cell RNA sequencing data (Keller)
- Design of biodegradable nanoparticles to modulate phenotypes of antigen presenting cells for antigen-specific treatment of autoimmune disease (Shea)
- Generation of human fatty livers using custom-engineered induced pluripotent stem cells with modifiable SIRT1 metabolism (D. Nagrath)
- Increased adhesive potential of antiphospholipid syndrome neutrophils mediated by beta‐2 integrin Mac‐1 (Eniola-Adefeso)
- Multiplex isolation and profiling of extracellular vesicle using microfluidic DICE device (S. Nagrath)
- Reactive oxygen species in the tumor microenvironment: An overview (D. Nagrath)
- Cargo-less nanoparticles program innate immune cell responses to toll-like receptor activation (Shea)
- Intravascular innate immune cells reprogrammed via intravenous nanoparticles to promote functional recovery after spinal cord injury (Shea)
- Knockdown of Notch1 inhibits nasopharyngeal carcinoma cell growth and metastasis via downregulation of CCL2, CXCL16, and uPA (Keller)
- Microporous scaffolds support assembly and differentiation of pancreatic progenitors into β-cell clusters (Shea)
Nanotechnology
- Colloidal fibers and rings by cooperative assembly (Glotzer)
- Diverse nanoassemblies of graphene quantum dots and their mineralogical counterparts (Kotov)
- Assembly of gold nanoparticles into chiral superstructures driven by circularly polarized light (Kotov)
- Stretchable batteries with gradient multilayer conductors (Kotov)
- Supraparticle nanoassemblies with enzymes (Glotzer & Kotov)
- The entropic bond in colloidal crystals (Glotzer)
- Energy landscapes for digital alchemy (Glotzer)
- Entropic colloidal crystallization pathways via fluid–fluid transitions and multidimensional prenucleation motifs (Glotzer)
- Letter to the Editor: Modeling the nonmonotonic time-dependence of viscosity bifurcation in thixotropic yield-stress fluids (Larson & Solomon)
- Modeling intercolloidal interactions induced by adsorption of mobile telechelic polymers onto particle surfaces (Larson)
- Terahertz circular dichroism spectroscopy of biomaterials enabled by kirigami polarization modulators (Kotov)
- Topological order in densely packed anisotropic colloids (Glotzer)