Nanostructured materials represent the one of the five technological pillars of the Biointerfaces Institute. The focus of this work is on simulating nanomaterial self-assembly and developing the different kinds of nanotubes, nanoprobes, nanocatalysts and nanostructures for applications in medicine, energy conversion, and electronics.
Biointerfaces Institute researchers use nanostructured materials in drug delivery, neural interface, rare cell detection, different imaging modalities, and microfluidics organ replicas. Research groups from UM Medical School or Biomedical Engineering department focusing on the end-use therapeutics or diagnostics utilize nanoparticles developed by BI research groups specializing in particle synthesis. Some of the nanomaterials that developed in BI are unique to UM. They include “janus” biodegradable nanoparticles, iron sulfide (FeS2) nanoparticles, aramid nanofibers (ANFs), and biomimetic composites. Examples of ongoing projects taking advantage of unique properties of nanomaterials developed at the Biointerface Institute include selective targeting of breast cancer cells, long-term implants for brain recording, artificial bone marrow, single cell metabolism monitoring with SERS-active nanoparticle assemblies, and others.
Basic research on nanomaterials that is expected to advance the field of biointerfaces in the next 5-10 years includes replication of protein functions by inorganic nanostructures, theory and practice of nanoparticle self-organization phenomena, DNA mechanics, high-speed computer simulations of nanoparticle dynamics, membrane-particle interactions, and wetting at nanoscale interfaces. Considerable effort is also invested in understanding the challenges for scaled up manufacturing nanoscale materials and devices by bridging nanotechnologies with different types of high-throughput lithography and microelectromechanical devices.
Related Press Releases & Articles
- June 22, 2018 / Press Release
Mike Solomon Appointed Dean of Rackham Graduate School
BI Faculty member and Chemical Engineering Professor Mike Solomon will serve as the next dean of Rackham Graduate School and vice provost for academic affairs-graduate studies.
- May 3, 2018 / Article
Tessier elected to the AIMBE College of Fellows Class of 2018
Peter Tessier was elected a Fellow of the American Institute for Medical and Biological Engineering (AIMBE). AIMBE comprises of leaders in medical and biological engineering, consisting of academic, industrial, professional society councils and elected fellows.
- May 1, 2018 / Award
Congratulations Microposter Winners
Thank you to all of the poster presenters who attended the BIRG 2nd Microposter Session and congratulations to our winners!
- April 16, 2018 / YouTube Video
Tuteja lab reports on new omniphobic coatings that repel almost everything
In a paper recently published in ACS Applied Materials & Interfaces, the Tuteja lab reports on recent findings on omniphobic coatings that could be applied on a variety of surfaces to repel almost any liquid.
- April 11, 2018 / Award
Kotov awarded Vannevar Bush Faculty Fellowship
Nick Kotov is one of members of the 2018 class of the Vannevar Bush Faculty Fellowship, awarded by the Department of Defense.
- March 1, 2018 / Article
Interdisciplinary team of BI researchers publish new article on 3-D Jet Writing Technique
The article entitled “3D Jet Writing: Functional Microtissues Based on Tessellated Scaffold Architectures” appears in Advanced Materials.
- February 22 @ 2:00 pm
Seminar on “Materials for Biodegradable Electronics” – John Rogers, Northwestern University
This event is co-hosted by the University of Michigan ACS POLY/PMSE Student Chapter and the Biointerfaces Institute Researcher Group.
- February 21, 2018 / YouTube Video
Kotov awarded Gold Prize Award in the Mobile World Scholar Challenge
Nick Kotov’s work on biomimetic composites is recognized by the Mobile World Scholar Challenge
- January 25, 2018 / Featured
New Science Article from the Kotov Lab
The article entitled “Chiromagnetic Nanoparticles and Gels” appeared in the January 19 issue of Science.
- January 23, 2018 / Press Release
Diabetes and Its Complications Challenge Seed Funds Awards
We are pleased to announce our selection for the Diabetes and Its Complications Challenge seed fund competition.
- November 29, 2017 / Press Release
Nanoparticles self-assemble into nanoshells
Research in the Kotov group demonstrated the self-assembly of inorganic nanoparticles into nanoshells, which can potentially be used for gene delivery applications. More details here.
- November 29, 2017 / Featured
Nick Kotov develops artificial cartilage materials from Kevlar-based nanofibers.
- November 5, 2017 / Press Release
Lee Lab – Bioplasmonics Group
The Bioplasmonics Group, directed by Prof. Somin Lee, works at the interface between life science, physical science and engineering, drawing from a combination of bottom-up and top-down nanofabrication approaches, to design and develop smart biophotonic technologies and uncover biological complexities in the development of tissues and in cancer. Specifically, they have recently developed novel tools, including an mechano-optical plasmonic nanoantenna, to measure the temperature of proteins in cells. Prof. Lee received a Young Investigator Award from the Air Force Office of Scientific Research (AFOSR) to support this research.
- October 24, 2017 / Article
Glotzer article in Langmuir
The Glotzer group published an article entitled “Virial Coefficients and Equations of State for Hard Polyhedron Fluids” in Langmuir.
- October 18, 2017 / Featured
Langmuir cover highlights research from Larson and Solomon
Research on controlled levitation of surface-modified colloids by electric fields was recently published in Langmuir and selected as the issue’s cover art. The work was performed in Ron Larson and Michael Solomon’s groups. Lead author, Carlos A. Silvera Batista, was a UM Presidential Postdoctoral Fellow in the Solomon lab and recently joined the Department of Chemical Engineering at Vanderbilt University as an Assistant Professor.
- October 16, 2017 / Article
The Kotov group reports on stretchable conductors
The article “Stretchable conductors by kirigami patterning of aramid-silver nanocomposites with zero conductance gradient” appeared in Applied Physics Letters.
- October 11, 2017 / Article
An article co-authored by Green, Larson and Solomon published in Physical Review Letters
Joint research in the Green, Larson and Solomon groups published in Physical Review Letters in an article entitled “Rheological State Diagrams for Rough Colloids in Shear Flow”.
- October 2, 2017 / Article
The Larson group reports on new computational models to study interactions within solid dispersion formulations
Their research findings appeared in Molecular Pharmaceutics in an article entitled “Multiscale Computational Modeling of the Nanostructure of Solid Dispersions of Hydroxypropyl Methylcellulose Acetate Succinate (HPMCAS) and Phenytion”.
- September 18, 2017 / Article
Report on the role of branched nanofibers in 3-dimensional networks
An article co-authored by N. Kotov and P. Green reports on the role of branched aramid nanofibers in three-dimensional network. The article appeared in Angewandte Chemie.