Dr. Sarah Spanninga in the Nanotechnicum using the Discovery 2500 Differential Scanning Calorimeter (DSC)

Nanotechnicum

The Biointerfaces Institute (BI) offers state-of-the-art instrumentation to its constituents, the UM research community, fellow academic institutions, and industry.

 

Particle Characterization

Mastersizer 2000

Usage: particle size distribution by laser diffraction with Hydro 2000S (range ~0.02 μm ‐600 μm)

Manufacturer: Malvern

 

Nanosight NS300

Usage: particle size distribution and concentration by nanoparticle tracking analysis (range ~10 nm -1 μm)

Manufacturer: Malvern

 

Zetasizer Nano ZSP

Usage: particle size distribution by dynamic light scattering ( range ~0.3 nm -10 μm) and zeta potential measurement

Manufacturer: Malvern

Zetaview TWIN

Usage: particle size distribution and concentration by nanoparticle tracking analysis (range 15 nm -1 μm) and zeta potential measurement

Manufacturer: Particle Metrix

Thermal Characterization

Discovery 2500 Differential Scanning Calorimeter (DSC)

Usage: thermal properties of materials, melting, glass transition temperatures, etc.

Manufacturer: TA Instruments

Discovery 5500 Thermal Gravimetric Analysis (TGA)

Usage: degradation behavior of materials

Manufacturer: TA Instruments

Nano DSC

Usage: quantifies biomolecule thermal stability by measuring thermal changes in biomolecules, like proteins, occurring during structural changes

Manufacturer: TA Instruments

Nano ITC

Usage: quantifies enthalpy or entropy of reactions, for example, protein-protein interactions, to determine binding constant (Ka) and reaction energy properties

Manufacturer: TA Instruments

Materials Characterization

J-815 Circular Dichroism (CD) spectrometer

Usage: chiral materials or secondary structures of proteins (range 163 nm -900 nm)

Manufacturer: Jasco

J-1700 Circular Dichroism (CD) Spectrometer

Usage: chiral materials or secondary structures of proteins (range 163 nm -2500 nm)

Manufacturer: Jasco

Circularly Polarized Luminescence Spectrometer (CPL-300)

Usage: excited chiral materials characterization (range 250 nm –850 nm)

Manufacturer: Jasco

IR-Tracer100 Fourier-Transform Infrared (FTIR)

Usage: materials characterization in the infrared (range 400 1/cm-4000 1/cm)

Manufacturer: Shimadzu

FluoroMax Plus spectrofluorometer

Usage: fluorescent materials characterization with near IR detector (range 185 nm-1550 nm)

Manufacturer: Horiba

Porosimeter Autopore V (Model: 9620)

Usage: Material porosity measurement by mercury intrusion for pore size distribution, pore volume etc. (pore size range ~0.003 μm -500 μm)

Manufacturer: Micromeritics

UM Internal Rates for using Nanotechnicum instruments

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